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Diagnostic imaging in Nuclear Medicine (NM) - mod. THERAPY TECHNIQUES MN
FABIO FRINGUELLI

Seat Medicina e Chirurgia
A.A. 2013-2014
Credits 2
Hours 20
Period 2^ semestre
Language ENG
U-gov code MT07-11-11 MT041

Prerequisites
Fundamentals about Radionuclides and Radiopharmacy

Development of the course
lessons with slides about program, references and early discussion.

Learning outcomes
: Good Knowledgde of Radionuclides use in Diagnostic Nuclear Medicine and in Radionuclide Therapy.

Program
- Fundamentals of Nuclear Pharmacy: Radioisotopes, Radionuclides, Alpha (á) Decay, Beta (â-) Decay, Positron or (â+) Decay, ã-ray emission. Radioactive Decay Equations. Instruments for Radiation Detection and Measurement.. - Production of Radionuclides. - Radionuclide Generator: 99Mo-99mTc Generator. - Definition of a Radiopharmaceutical. - Ideal Radiopharmaceutical, Biodistribution. - Methods of Radiolabeling and Important Factors in Labeling. - Labeling with 99mTc. - Characteristics of Specific Radiopharmaceuticals. - Radioiodinaded Radiopharmaceuticals. - Miscellaneus Radiopharmaceuticals of Clinical Interest. - PET Radiopharmaceuticals: Biochemistry and Biodistribution. - Quality Control of Radiopharmaceuticals. - Chromatography. - Fundamentals in Radionuclide Therapy. - Treatment of Hyeprthyrodism. - Treatment of Differentiated Thyroid Cancer. - Treatment of Pain Secondary to Scheletal Metastases. - Treatment of Neuroendocrine Tumors. - Radioimmunotherapy. - Radionuclide Synoviectomy. - Other Therapeutic Procedures. - Biological Effects of Ionizing Radiation. - Short assay in Radiopharmacy Regulations. - Molecular Imaging: emerging discipline.

Development of the examination
oral examination, possible written examination.

Recommended reading
1. TITLE: FONDAMENTI DI MEDICINA NUCLEARE AUTHOR: Volterrani, Erba, Mariani PUBLISHER: Springer 2. TITLE THE PATHOPHYSIOLOGYC BASIS OF NUCLEAR MEDICINE AUTHOR Abdelhamid Elgazzar PUBLISHER: Springer 3. TITLE: TECHNETIUM-99m PHARMACEUTICALS AUTHOR: TECHNETIUM-99m PHARMACEUTICALS PUBLISHER: Springer 4. EANM: Radiopharmacy Guidelines. 5. EANM: Radionuclide Therapy Guidelines. 6. AIMN: Raccomandazioni procedurali 7. AIMN: Le norme di buona preparazione dei radiofarmaci in Medicina Nucleare 8. ACR-SNM:Technical standards for diagnostic procedures using radiopharmaceuticals

Courses

• Tecniche di Radiologia Medica, per Immagini e Radioterapia