Facoltà di Medicina e Chirurgia - Guida degli insegnamenti (Syllabus)
The aim of the course is to allow the students to acquire a basic knowledge of chemistry and molecular biology, in order to understand the processes of living organisms.
At the end of the course the student will know the fundamental concepts of general chemistry, which are needed in order to address different professional fields, the basic principles of organic chemistry, the chemistry of functional groups, as well as the main reaction mechanisms of organic compounds. The student will also be aware of the structure and properties of biomolecules involved in the storage, transmission and expression of genetic information and the molecular mechanisms that underlie these processes. The knowledge of the fundamentals of molecular biology will allow the student to understand the biotechnological applications of this discipline and the resulting impact on medicine and diagnostics.
States of matter: gas, liquid and solid. Solutions: concentration and colligative properties.
Atoms and chemical bonds. Atomic weight and mole. Electron configuration of atoms. Ionic bond, covalent bond and molecules. Bond energy, bond length, multiple bonds, resonance structures, electronegativity, polar bonds, dipoles, coordinative bond. Molecular orbitals, σ bond, π bond, valence bond theory.
Chemical reactions: chemical equations, oxidation number, oxidation-reduction reactions. Equivalent weight and normality.
Thermodynamic principles. Free energy.
Chemical kinetics and equilibrium. Homogeneous and heterogeneous reactions. Reaction rate. Rate constants and rate law. Activation energy, activated-complex theory.
Chemical equilibrium: equilibrium constant and mass action law. Arrhenius equation. Catalyzers. Acids and bases. Ionic product of water and pH. Salt hydrolysis, buffer solutions. Acid-base titrations, pH-indicators. Coordination compounds.
Oral exam on the course subjects.
Titolo: Chimica e propedeutica biochimica.
Autore: A. Fiecchi
Casa Editrice: Edi. Ermes
Titolo: Chimica di base per le scienze della vita.
Autore: M. Anastasia
Casa Editrice: Antonio Delfino Editore.
Università Politecnica delle Marche
P.zza Roma 22, 60121 Ancona
Tel (+39) 071.220.1, Fax (+39) 071.220.2324
P.I. 00382520427