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Biology and Biochemestry - mod. BIOLOGY (PU)
FRANCESCO PIVA

Seat Medicina e Chirurgia
A.A. 2013-2014
Credits 2
Hours 24
Period 1^ semestre
Language ENG
U-gov code MT02-11-11 MT128

Prerequisites
Basic knowledge of Biology and Chemistry

Development of the course
The course aims to contribute to the training of a nurse who knows the working of the cell, the main mechanisms of genetic expression and regulation, the main mechanisms controlling cell division and differentiation, the modality of transmission of hereditary characters and mechanisms that can lead to phenotypic variants in humans.

Learning outcomes

At the end of the course the student should know:
1. the fundamental characteristics of living matter and the molecular and functional organization of the cell
2. the main types of communication among cells in multicellular organisms and some mechanisms of signal transduction
3. the main mechanisms to interpret the genetic information
4. the main laws of genetic transmission of hereditary characteristics
5. the difference between mutations in the germ cells and somatic cells, their possible consequences.

Program

The transduction of receptor signal
Mitochondria and other cellular organelles; rough and smooth endoplasmic reticulum, Golgi apparatus.
Cytoskeleton and cell motility.
Mitosis and meiosis, cell reproduction, cell cycle.
Chromosomes and chromatin.
The evolution from prokaryotes to eukaryotes. Evolution of cellular functions, of cellular reactions. Cell differentiation.
Cell membranes: composition, structure and function.
Characteristics of living organisms.
Transcription in prokaryotes and eukaryotes; translation in prokaryotes and eukaryotes.
Structure of nucleic acids. DNA, DNA duplication in prokaryotes and eukaryotes.
Regulation of gene expression, DNA repair mechanisms. RNA: structures and functions.
Evolutionary and population genetics.
Mutations: the variability. Inheritance. Locus. Alleles. Multiple alleles.
Genes. Phenotype and genotype.
Mendel's laws, non-mendelian inheritance. Epistasis.
The blood groups.
Polygeny and polymorphisms.
Abnormalities in chromosome structure and their pathogenic mechanisms.
Molecular bases of genetic diseases.
Analyses of gene mutations in humans.
Not-hereditary congenital diseases.

Development of the examination
Oral examination

Recommended reading

a)     TITLE: Chimica Biochimica e Biologia Applicata

b)     AUTHOR: Stefani - Taddei

c)      PUBLISHER. Zanichelli

Courses

• Infermieristica Pesaro