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Biochemistry - C.I. (I ANNO)
LAURA MAZZANTI

Seat Medicina e Chirurgia
A.A. 2017-2018
Credits 12
Hours 120
Period 2^ semestre
Language ENG
U-gov code MU01-09-11 LS058

Prerequisites

Knowledge of biology, physics and cell chemistry. 

Development of the course

The course is articulated in frontal lessons, Seminars and, Exercises theoretical-practices and formality and-learning Technology Enhanced.

Learning outcomes

• Knowledge

The student should have developed the ability to understand the basics of the molecular structure and organization of the main biomolecules, as well as to know the basics of bioenergetics and the general meaning of metabolism. It should also be able to interpret the nutritional and nutritional requirements in humans. The student will also have to know the metabolism of all human organs.

• Ability to apply the knowledge

The subjects of the program are necessary to apply practical knowledge to the profession of dental practice and to understand also the topics that will be subsequently proposed for acquiring the skills provided by other courses (eg Physiology, Pharmacology, Pathology etc.) in the field of dentistry training and therefore for an optimal development of the student's professionalism. The student, through the support of the recommended texts and / or the consultation of the scientific literature, will be able to critically learn advanced topics related to the issues related to development and biochemical applications in the medical field.The subjects of the program are necessary to apply practical knowledge to the exercise of the medical profession and to understand also the topics that will be subsequently proposed for the acquisition of the skills provided by other courses (eg Physiology, Pharmacology, Pathology, Clinical Biochemistry, etc.) in the field of training in Medicine and Surgery and therefore for an optimal development of the student's professionalism. The subjects of the program are necessary to apply practical knowledge to the exercise of the medical profession and to understand also the topics that will be subsequently proposed for the acquisition of the skills provided by other courses (eg Physiology, Pharmacology, Pathology, Clinical Biochemistry, etc.) in the field of training in Medicine and Surgery and therefore for an optimal development of the student's professionalism.

• Soft skills

Through the acquisition of the anticipated knowledges from the Course of Biochemistry, and thanks to the ability to understand the application of the same in professional circle, the student is able to acquire useful further competences of transversal character for the understanding of simple clinical cases that you/they can be introduced in specialistic circle as the medicine of urgency, fisio-pathological aspects of the chronic-degenerative illnesses dismetaboliche (diabetes, obesity, metabolic syndrome). The attention posts on the importance of an approach multidisciplinare and the didactic formulation of the course, that a solid conjugates to know to a suitable to know how to say and to know how to do, stimulates the logical abilities and it creates the psychological motivations that the student stimulates continuously to the search improvement and they makes

Program

mod. BIOCHEMISTRY AND METABOLIC BIOCHEMISTRY

Prof. L. Mazzanti

Metabolic pathways :  The anaerobic glycolysis and pyruvate oxidation,  Krebs cycle and oxidative phosphorylation, pentose  shunt  and reduced coenzymes production,  glycogen metabolism, gluconeogenesis, glucosehomeostasis, fatty acid oxidation, ketogenesis, fatty acid biosynthesis , triglycerides and phospholipids, cholesterol and lipoprotein metabolism, transamination and    glutamate deamination, urea cycle and glutamine synthesis and  degradation of  nucleobases: uric acid. Synthesis and elimination of bile pigments: plasma bilirubin. Metabolism of organs and tissues and their functional correlations.

mod. GENERAL BIOCHEMISTRY

Prof.ssa G. Ferretti

Lipids, carbohydrates and proteins in food. General functions of enzymes and enzyme kinetics. Coenzymes used in metabolic reactions and biochemical actionof vitamins. Structure and function of hemoglobin and myoglobin and their functions of binding and transporting oxygen.

Bioenergetics and biological oxidation: ATP. Biochemical mechanisms of regulation of major metabolic pathways. Biochemistry of the endocrine system: relationship between structure and function of  different hormones (non-protein and protein) and their role in metabolism. General principles of digestion  and absorption  of food,  as vectors of nutrients,  antinutrients and nutrients. Biochemical and pathophysiological parameters of foods.

 

 

Development of the examination

• Methods for assessing learning outcomes:

Being an Integrated Course, the overall assessment of profit can not be divided into separate evaluations on individual lessons or modules and will be expressed collectively by teaching professors. The related credits will therefore be acquired only after the overall evaluation of both modules. The commission is made up of both the two modules belonging to the integrated course and, if one is not available, by an alternate. The assessment of the learning is done by oral examination with the discussion of 4 topics related to the program of the two modules.

Admission to the oral examination is subject to completion of the activities delivered in the e-learning mode, according to the specific terms communicated by the teachers at the beginning of the integrated course lessons.

• Criteria for assessing learning outcomes: 

In the oral exam, the student must demonstrate that he / she is able to use the appropriate terminology useful for correct and strictly scientific communication in the general biochemical and metabolic aspects. Learning assessment tests are designed to evaluate acquired knowledge and skills. Through oral tests, critical capacity, self-learning and verbal communication are also evaluated.

• Criteria for measuring learning outcomes:

The final vote is articulated in thirty-five and will be exceeded when the vote is equal to or greater than 18/30. It is also possible to award the praise in the presence of a final vote of not less than 30/30.

• Criteria for conferring final mark:

The final vote is given by calculating the average of the evaluation of individual questions. Praise is given when the student has obtained a final vote of not less than 30/30, has demonstrated full mastery of the subject and there is unanimity in the Commission.

Recommended reading

           Prof. L. Mazzanti and Prof. G. Ferretti.

• Title: Biochimica; Author: R.H. Garrett, C.M. Grisham; Publisher: 5° edizione Piccin
• Title: Biochimica per le discipline biomediche; Author: Baynes – Dominiczak; Publisher: Elsevier
• Title: Biochimica con aspetti clinici; Author: Devlin; Publisher: 5° edizione Edises

PROFESSOR CONTACT:

Prof. Laura Mazzanti Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche - Sezione Biochimica, Biologia e Fisica 071.2206014 - 071.2204675 E-mail: l.mazzanti@ staff. univpm.it

Prof. Gianna Ferretti Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche - Sezione Biochimica, Biologia 071-2204968-0712204672 E-mail: g.ferretti@staff.univpm.it

 

OFFICE HOURS:

Prof. Laura Mazzanti every day after a telephone appointment or by email
Polo Didattico Monte Dago o Polo Didattico Torrette - Dipartimento DISCO 

Prof. Gianna Ferretti every day after a telephone appointment or by email Polo Didattico Monte Dago o Polo Didattico Torrette - Dipartimento DISCO 

Courses

• Medicina e Chirurgia